Organism_bioentity1_name Bioentity1_type Bioentity1_common_name Bioentity1_canonical_name Bioentity1_full_name Bioentity1_aliases Bioentity1_location Bioentity1_state Bioentity1_regulatory_feature Interaction_type Organism_bioentity2_name Bioentity2_common_name Bioentity2_canonical_name Bioentity2_full_name Bioentity2_aliases Bioentity2_type Bioentity2_regulatory_feature Bioentity2_location Interaction_group Confidence_score Interaction_description Assay_name Assay_type Publication_ids Mouse Protein TLR1 NM_030682 "membrane, plasma" interacts with bacteria triacyl-lipopeptide small molecule extracellular TIR Module "Biological, KO" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein TLR2 NM_011905 "membrane, plasma" interacts with bacteria triacyl-lipopeptide small molecule extracellular TIR Module "Biological, KO" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein TLR2 NM_011905 "membrane, plasma" interacts with bacteria diacyl-lipopeptide small molecule extracellular TIR Module "Biological, KO" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein TLR3 NM_126166 membrane interacts with viridae dsRNA RNA extracellular TIR Module "Biological, KO" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein TLR4 NM_021297 membrane interacts with bacteria LPS small molecule extracellular TIR Module "Biological, KO, genetic" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein TLR5 NM_016928 membrane interacts with bacteria flagellin D13689 protein extracellular TIR Module "Biological, KO, IP" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein TLR6 NM_011604 "membrane, plasma" interacts with eubacteria diacyl-lipopeptide small molecule extracellular TIR Module "Biological, KO" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein TLR7 NM_133211 membrane interacts with synthetic R-848 small molecule extracellular TIR Module "Biological, KO" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein TLR8 NM_133212 membrane interacts with synthetic R-848 small molecule extracellular TIR Module "Biological, KO" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein TLR9 NM_031178 membrane interacts with "bacteria, viridae" CpG DNA DNA extracellular TIR Module "Biological, KO, genetic" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein TLR4 NM_021297 membrane interacts with CD14 NM_021297 Protein "membrane, plasma" TIR Module "Biological, KO" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein TLR4 NM_021297 membrane interacts with MD-2 NM_009841 Protein "membrane, plasma" TIR Module "Biological, KO, IP" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein CD14 NM_009841 membrane interacts with bacteria LPS small molecule extracellular TIR Module "Biological, KO, genetic" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein MD-2 NM_016923 membrane interacts with bacteria LPS small molecule extracellular TIR Module "Biological, KO, genetic" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein LBP NM_008489 membrane interacts with bacteria LPS small molecule extracellular TIR Module "Biological, KO, genetic" 12524386 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein AOAH NM_012054 secreted inhibits bacteria LPS small molecule extracellular TIR Module "Biological, KO, genetic" 2549069 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein IRAK4 NM_029926 cytosol "interacts with, ligand-induced" Mouse IRAK1 NM_008363 Protein cytosol TIR Module IP 11960013 interaction is not specified Mouse Protein IRAK4 NM_029926 cytosol "interacts with, ligand-induced" Mouse MyD88 NM_010851 Protein cytosol TIR Module IP 11960013 interaction is not specified Mouse Protein IRAK4 NM_029926 cytosol "interacts with, ligand-induced" Mouse TRAF6 NM_009424 Protein cytosol TIR Module "IP, structure" 11960013 interaction is not specified Mouse Protein TRAF6 NM_009424 cytosol interacts with Mouse RANK NM_009399 Protein "membrane, plasma" TIR Module "IP, structure" 10635328 "IP, structure": assayType is not in the database Mouse Protein TRAF6 NM_009424 cytosol interacts with Mouse CD40 NM_011611 Protein "membrane, plasma" TIR Module structure 12140561 Structure: assayType is not in the database Mouse Protein TRAF6 NM_009424 cytosol interacts with Mouse IRAKM NM_028679 Protein cytosol TIR Module structure 12140561 Structure: assayType is not in the database Mouse Protein TRAF6 NM_009424 cytosol interacts with Mouse IRAK1 NM_008363 Protein cytosol TIR Module structure 12140561 Structure: assayType is not in the database Mouse Protein TIFA NM_145133 cytosol interacts with Mouse TRAF6 NM_009424 Protein cytosol TIR Module IP 12566447 IP: assayType is not in the database Mouse Protein TIFA NM_145133 cytosol interacts with Mouse IRAK1 NM_008363 Protein cytosol TIR Module IP 12566447 IP: assayType is not in the database Mouse Protein TAK1 NM_172688 cytosol "phosphorylates, S177/S181" Mouse IKKB AF088910 Protein cytosol TIR Module 11460167 interaction is not specified Mouse Protein TAK1 NM_172688 cytosol "phosphorylates, S207/T211" Mouse MKK6 XM_126577 Protein cytosol TIR Module 11460167 interaction is not specified Mouse Protein UBIQUITIN NM_019639 "conjugated to, K63 polyubiquitin" Mouse TRAF6 NM_009424 Protein cytosol TIR Module 11460167 interaction is not specified Mouse Protein A20 NM_009397 cytosol interacts with Mouse TRAF6 NM_009424 Protein cytosol TIR Module IP 9928991 IP: assayType is not in the database Mouse Protein A20 NM_009397 cytosol interacts with Mouse TRAF1 NM_009421 Protein cytosol TIR Module IP 8692885 IP: assayType is not in the database Mouse Protein A20 NM_009397 cytosol interacts with Mouse TRAF2 XM_130119 Protein cytosol TIR Module IP 8692885 IP: assayType is not in the database Mouse Protein FADD NM_010175 cytosol Mouse I-FLICE NM_009805 Protein cytosol TIR Module interactionType is not specified Mouse Protein FADD NM_010175 cytosol Mouse FAS NM_007987 Protein "membrane, plasma" TIR Module interactionType is not specified Mouse Protein FADD NM_010175 cytosol Mouse DR3 Protein "membrane, plasma" TIR Module interactionType is not specified Mouse Protein FADD NM_010175 cytosol Mouse TNFR1 Protein "membrane, plasma" TIR Module interactionType is not specified DR3 TRADD TIR Module Y2H 8934525 bioentity1_type or organism1 is not defined TNFR1 TRADD TIR Module Y2H 7758105 bioentity1_type or organism1 is not defined TRADD TRAF2 TIR Module Structure 10892748 bioentity1_type or organism1 is not defined TRADD TRAF1 TIR Module Structure 10892748 bioentity1_type or organism1 is not defined c-IAP1 interacts with TRAF1 TIR Module 8548810 bioentity1_type or organism1 is not defined c-IAP2 interacts with TRAF1 TIR Module 8548810 bioentity1_type or organism1 is not defined c-IAP1 interacts with TRAF2 TIR Module 8548810 bioentity1_type or organism1 is not defined c-IAP2 interacts with TRAF2 TIR Module 8548810 bioentity1_type or organism1 is not defined Mouse Protein TNFR1 "membrane, plasma" "interacts with, PLAD domain" Mouse TNFR1 Protein "membrane, plasma" TIR Module 10875917 interaction is not specified Mouse Protein TNFR2 "membrane, plasma" "interacts with, PLAD domain" Mouse TNFR2 Protein "membrane, plasma" TIR Module 10875917 interaction is not specified Mouse Protein TNFR1 "membrane, plasma" interacts with PIP5K TIR Module 9038203 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database PIP5K "interacts with, substrate" PIP1(4) small molecule TIR Module bioentity1_type or organism1 is not defined PIP5K "interacts with, product" "PIP2(4,5)" small molecule TIR Module bioentity1_type or organism1 is not defined c-IAP1 ubiquitnates TRAF2 TIR Module 11907583 bioentity1_type or organism1 is not defined UBIQUITIN conjugated to TRAF2 TIR Module 11907583 bioentity1_type or organism1 is not defined UBCH7 ubiquitnates TRAF2 TIR Module 11907583 bioentity1_type or organism1 is not defined UBCH7 interacts with UBIQUITIN TIR Module 11907583 bioentity1_type or organism1 is not defined c-IAP1 interacts with UBIQUITIN TIR Module 11907583 bioentity1_type or organism1 is not defined Mouse "Protein, ubiquitinated" TRAF2 cytosol degraded by Mouse 26S Proteasome complex TIR Module 11907583 bioentity1_type or organism1 is not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined Mouse Protein AKT1 NM_009652 cytosol "phosphoryales, S23" Mouse IKKA NM_007700 Protein cytosol TIR Module 10485710 interaction is not specified Mouse Protein NIK cytosol "phosphoryales, S176" Mouse IKKA NM_007700 Protein cytosol TIR Module 10485710 interaction is not specified Mouse Protein IKKB AF088910 cytosol "phosphorylates, S32/S36" Mouse NFIKBA NM_010907 Protein "cytosol, nucleus" TIR Module 9346485 interaction is not specified small molecule salicylate inhibits Mouse IKKB AF088910 Protein cytosol TIR Module 9817203 bioentity1_type or organism1 is not defined Mouse Protein IKKB AF088910 cytosol "autophosphorylates, C-terminal Ser cluster" Mouse IKKB AF088910 Protein cytosol TIR Module 10195894 interaction is not specified Mouse Protein Caspase-3 cytosol "inhibits, proteolyzes D78/D242/D373/D546 " Mouse IKKB AF088910 Protein cytosol TIR Module 11741536 interaction is not specified small molecule PGE inhibits Mouse IKKB AF088910 Protein cytosol TIR Module 10638762 bioentity1_type or organism1 is not defined Mouse Protein NFIKBA NM_010907 "cytosol, nucleus" inhibits Mouse NFKB1p50 Protein "cytosol, nucleus" TIR Module "Structure, IP" "Structure, IP": assayType is not in the database Mouse Protein NFIKBA NM_010907 "cytosol, nucleus" inhibits Mouse RELA NM_009045 Protein "cytosol, nucleus" TIR Module "Structure, IP" "Structure, IP": assayType is not in the database Mouse Protein NFIKBA NM_010907 "cytosol, nucleus" TIR Module bioentity2 is not specified, bioentity1 has been added to the database Mouse Protein NFIKBA NM_010907 "cytosol, nucleus" TIR Module bioentity2 is not specified, bioentity1 has been added to the database Mouse Protein NFKB1p50 NM_008689 "cytosol, nucleus" interacts with Mouse RELA NM_009045 Protein "cytosol, nucleus" TIR Module "Structure, IP" "Structure, IP": assayType is not in the database Mouse Protein NFIKBL1 NM_010909 nucleus ? TIR Module bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein NFKB1p105 NM_008689 cytosol inhibits TPL2 NM_007746 TIR Module bioentity2_type or organism2 is not defined, bioentity1 has been added to the database PKA NM_008854 "phosphorylates, S276" Mouse RELA NM_009045 Protein "cytosol, nucleus" TIR Module 9660950 bioentity1_type or organism1 is not defined Mouse Protein NFIKBA NM_010907 "cytosol, nucleus" not interact with Mouse RELA NM_009045 "Protein, acetylated" nucleus TIR Module bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein HDAC3 NM_010411 nucleus deacetylates Mouse RELA NM_009045 "Protein, acetylated" nucleus TIR Module bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein CRM1 NM_134014 "nucleus, cytosol" interacts with RAN "Protein, GTP" nucleus TIR Module 9323133 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined Mouse "Protein, phosphorylated S133" CREB nucleus interacts with Mouse CBP Protein nucleus TIR Module 7913207 bioentity1_type or organism1 is not defined Mouse Protein PKA NM_008854 "phosphorylates, S133" Mouse CREB Protein nucleus TIR Module 7913207 interaction is not specified Mouse small molecule cAMP activates Mouse PKA Protein TIR Module bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated S73/S63" JUN nucleus interacts with Mouse CBP Protein nucleus TIR Module 8028671 bioentity1_type or organism1 is not defined IKKE IRF3 TIR Module bioentity1_type or organism1 is not defined TBK1 IRF3 TIR Module bioentity1_type or organism1 is not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined Mouse Protein NFKB1p105 NM_008689 cytosol "stabilizes, inhibits" Mouse TPL2 NM_007746 Protein cytosol TIR Module KO 12667451 interaction is not specified Mouse Protein TPL2 NM_007746 cytosol phosphorylates Mouse MEK1 Protein cytosol TIR Module KO 11163183 KO: assayType is not in the database Mouse Protein TPL2 NM_007746 "interacts with, indirect, nucleocytoplasmic transport" Mouse TNF "RNA, ARE" nucleus TIR Module 11163183 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse "Protein, phosphorylated" ERK2 nucleus interacts with Mouse ERK2 "Protein, phosphorylated" nucleus TIR Module 9604935 bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated" ERK1 nucleus interacts with Mouse ERK1 "Protein, phosphorylated" nucleus TIR Module 9604935 bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated" ERK2 nucleus phosphorylates Mouse MNK1 Protein TIR Module 9155017 bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated" ERK1 nucleus phosphorylates Mouse MNK1 Protein TIR Module 9155017 bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated" ERK2 nucleus phosphorylates Mouse MNK2 Protein TIR Module 9155017 bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated" ERK1 nucleus phosphorylates Mouse MNK2 Protein TIR Module 9155017 bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated" ERK2 nucleus phosphorylates Mouse MSK1 Protein nucleus TIR Module 9687510 bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated" JNK2 nucleus phosphorylates Mouse MSK1 Protein nucleus TIR Module 9687510 bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated" MSK1 nucleus "phosphorylates, S133" Mouse CREB Protein nucleus TIR Module 9687510 bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated" p38alpha nucleus "phosphorylates, S78/S81" Mouse CHOP Protein nucleus TIR Module 8650547 bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated" p38alpha nucleus "phosphorylates, S78/S81" Mouse MEF2C Protein nucleus TIR Module 9069290 bioentity1_type or organism1 is not defined Mouse Protein TAB1 NM_025609 cytosol "interacts with, activates" Mouse p38alpha Protein TIR Module 11847341 interaction is not specified Mouse "Protein, phosphorylated" MK2 nucleus "phsophorylates, S86" Mouse HSP25 Protein TIR Module 1332886 bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated" p38alpha nucleus "phosphorylates, S78/S81" Mouse MK2 Protein TIR Module 1327754 bioentity1_type or organism1 is not defined Mouse "Protein, phosphorylated" MK2 nucleus phosphorylates Mouse PABP1 Protein TIR Module 12565831 bioentity1_type or organism1 is not defined Mouse Protein PABP1 interacts with Mouse TNF "RNA, ARE" TIR Module 12565831 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein eIF-4E interacts with Mouse 5'mRNA-Cap ubiqutious biological structure TIR Module bioentity2_type or organism2 is not defined, bioentity1 has been added to the database MNK1 "phosphorylates, S209" eIF-4E TIR Module 9878069 bioentity1_type or organism1 is not defined AUF1 interacts with TNF "RNA, ARE" TIR Module bioentity1_type or organism1 is not defined AUF1 interacts with MYC "RNA, ARE" TIR Module bioentity1_type or organism1 is not defined AUF1 interacts with FOS "RNA, ARE" TIR Module bioentity1_type or organism1 is not defined AUF1 interacts with GMCSF "RNA, ARE" TIR Module bioentity1_type or organism1 is not defined AUF1 interacts with HSC70 TIR Module 10205060 bioentity1_type or organism1 is not defined AUF1 interacts with HSP70 TIR Module 10205060 bioentity1_type or organism1 is not defined AUF1 interacts with eIF-4G TIR Module 10205060 bioentity1_type or organism1 is not defined AUF1 interacts with Mouse UBIQUITIN NM_019639 Protein TIR Module 10205060 bioentity1_type or organism1 is not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined TIR Module bioentity1_type or organism1 is not defined Mouse Protein BTRC ubiquitinates CTNNB1 "Protein, phosphorylated " TIR Module 9990852 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein BTRC ubiquitinates NFKBIA "Protein, phosphorylated S32/S36" TIR Module 9990852 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined Mouse Protein NEMO NM_178590 cytosol interacts with RIP TIR Module 9927690 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein NEMO NM_178590 cytosol interacts with NIK TIR Module 9927690 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein NEMO NM_178590 cytosol interacts with Adenovirus E3-14.7K Protein cytosol TIR Module 9927690 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined IKKE "phosphorylates, S36" NFIKBA TIR Module 10882136 bioentity1_type or organism1 is not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined Mouse Protein AKT1 NM_009652 cytosol phosphorylates BAD TIR Module bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein AKT1 NM_009652 cytosol phosphorylates Caspase-9 TIR Module bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein AKT1 NM_009652 cytosol phosphorylates FKHRL1 TIR Module bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein AKT1 NM_009652 cytosol "phosphorylates, S58" 14-3-3-zeta TIR Module 11956222 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein AKT1 NM_009652 cytosol interacts with PIP3 TIR Module bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein AKT1 NM_009652 cytosol "phosphorylates, S1177" eNOS TIR Module 10376603 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein AKT1 NM_009652 cytosol "phosphorylates, T236" EDG1 TIR Module 11583630 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein AKT1 NM_009652 cytosol phosphorylates GSK3B TIR Module bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein AKT1 NM_009652 cytosol "inhibits, phosphorylates" TSC2 TIR Module 12172554 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database Mouse Protein AKT1 NM_009652 cytosol "inhibits, phosphorylates T157" p27(KIP1) TIR Module 12244301 bioentity2_type or organism2 is not defined, bioentity1 has been added to the database TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined TSC2 NM_011647 interacts with TSC1 NM_022887 TIR Module 12172554 bioentity1_type or organism1 is not defined TSC1 NM_022887 interacts with mTOR NM_020009 TIR Module bioentity1_type or organism1 is not defined TSC2 NM_011647 interacts with mTOR NM_020009 TIR Module bioentity1_type or organism1 is not defined CTMP inhibits Mouse AKT1 NM_009652 Protein cytosol TIR Module 11598301 bioentity1_type or organism1 is not defined PDK1 NM_011062 "phosphorylates, S308" Mouse AKT1 NM_009652 Protein cytosol TIR Module bioentity1_type or organism1 is not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined PI3KG "phosphorylates, substrate" PIP2 small molecule TIR Module bioentity1_type or organism1 is not defined PI3KG "phosphorylates, product" PIP3 small molecule TIR Module bioentity1_type or organism1 is not defined PI3KA "phosphorylates, substrate" PIP2 small molecule TIR Module bioentity1_type or organism1 is not defined PI3KA "phosphorylates, product" PIP3 small molecule TIR Module bioentity1_type or organism1 is not defined PIK3R1 interacts with PI3KG TIR Module bioentity1_type or organism1 is not defined PIK3R1 interacts with PI3KA TIR Module bioentity1_type or organism1 is not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined SHIP "dephosphorylates, substrate" PIP3 TIR Module bioentity1_type or organism1 is not defined PTEN "dephosphorylates, substrate" PIP3 TIR Module bioentity1_type or organism1 is not defined "dephosphorylates, product" TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined "dephosphorylates, product" TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined Mouse Protein TRAM NM_173394 cytosol TIR Module bioentity2 is not specified, bioentity1 has been added to the database TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined TIR Module bioentity1_common_name and bioentiy_canonical_name are not defined Mouse Protein TRIF cytosol Mouse TBK1 Protein cytosol TIR Module interactionType is not specified Mouse Protein TRIF cytosol Mouse IKKE Protein cytosol TIR Module interactionType is not specified Mouse Protein TANK cytosol Mouse NEMO Protein cytosol TIR Module interactionType is not specified Mouse Protein NEMO cytosol Mouse TBK1 Protein cytosol TIR Module interactionType is not specified Mouse Protein NEMO cytosol Mouse IKKE Protein cytosol TIR Module interactionType is not specified